Glute (buttock) injection is a universal procedure that is
commonly used around the world. Selecting the proper site that avoids injury to
the neurovascular structures is important. The sciatic nerve could be at risk
for injury during a buttock injection. The buttocks is divided into quadrants. Divide
the buttock halfway down the middle and halfway across. Injection is given in the center of the upper
outer quadrant. Avoid the other quadrants. Injection into the other quadrants
may cause injury to the neurovascular structures and damage the sciatic
nerve. Another helpful method that could
confirm a safe site for injection is to draw a line from the posterior superior
edge of the iliac spine to the greater trochanter. This area above the line is
considered to be the safe zone for intramuscular injection.